Brent Chen

 

 

 

 

 

 

 

• 6th year Ph.D. candidate

• Education: B.S Biology, UNC Chapel Hill; MS Biological Sciences, Univ. of Southern Mississippi

• Lab: Mackay lab

• Fun fact: My family owns 15+ chickens.

• Email: qchen14@ncsu.edu

• Presentations:

  • The Allied Genetics Conference 2016
  • Gordan Research Conference in Epigenetics, 2017

• Publications:

  1. Vielle, A., Lang, J., Dong, Y., Ercan, S., Kotwaliwale, C., Rechtsteiner, A., Appert, A.,Chen, Q.B., Dose, A., Egelhofer, T., Kimura, H., Stempor, P., Dernburg, A., Lieb, J.D., Strome, S., Ahringer, J., 2012. H4K20me1 Contributes to Downregulation of X-Linked Genes for  elegans Dosage Compensation. PLoS Genetics 8, e1002933. PMCID: PMC3441679
  2. Chen, R.A.J., Down, T.A., Stempor, P.,Chen, Q.B., Egelhofer, T.A., Hillier, L.W., Jeffers, T.E., Ahringer, J., 2013. The landscape of RNA polymerase II transcription initiation in  elegans reveals promoter and enhancer architectures. Genome Research 23, 1339–1347. PMCID: PMC3730107
  3. Das, S.,Chen, Q.B., Saucier, J.D., Drescher, B., Zong, Y., Morgan, S., Forstall, J., Meriwether, A., Toranzo, R., Leal, S.M., 2013. The Drosophila T-box transcription factor Midline functions within the Notch-Delta signaling pathway to specify sensory organ precursor cell fates and regulates cell survival within the eye imaginal disc. Mechanisms of Development 130, 577-601. PMCID: PMC4500660
  4. Ho, J.W., Jung, Y.L., Liu, T., Alver, B.H., Lee, S., Ikegami, K., Sohn, K.A., Minoda, A., Tolstorukov, M.Y., Appert, A., Parker, S.C., Gu, T., Kundaje, A., Riddle, N.C., Bishop, E., Egelhofer, T.A., Hu, S.S., Alekseyenko, A.A., Rechsteiner, A., Asker, D., Belsky, J.A., Bowman, S.K.,Chen, Q.B., Chen, R.A., Day, D.S., Dong, Y., Dose, A.C., Duan, X., Epstein, C.B., Ercan, S., Feingold, E.A., Ferrari, F., Garrigues, J.M., Gehlenborg, N., Good, P.J., Haseley, P., He, D., Herrmann, M., Hoffman, M.M., Jeffers, T.E., Kharchenko, P.V., Kolasinska-Zwierz, P., Kotwaliwale, C.V., Kumar, N., Langley, S.A., Larschan, E.N., Latorre, I., Libbrecht, M.W., Lin, X., Park, R., Pazin, M.J., Pham, H.N., Plachetka, A., Qin, B., Schwartz, Y.B., Shoresh, N., Stempor, P., Vielle, A., Wang, C., Whittle, C.M., Xue, H., Kingston, R.E., Kim, J.H., Bernstein, B.E., Dernburg, A.F., Pirrotta, V., Kuroda, M.I., Noble, W.S., Tullius, T.D., Kellis, M., MacAlpine, D.M., Strome, S., Elgin, S.C., Liu, X.S., Lieb, J.D., Ahringer, J., Karpen, G.H., Park, P.J., 2014. Comparative analysis of metazoan chromatin organization. Nature 512, 449-452. PMCID: PMC4227084
  5. Chen, Q.B., Das, S., Visic, P., Buford, K.D., Zong, Y., Buti, W., Odom, K.R., Smith, R.S., Morgan, S., Leal, S.M., 2015. TheDrosophila T-box transcription factor Midline functions within Insulin/Akt and c-Jun-N-terminal kinase stress-reactive signaling pathways to regulate interommatidial bristle formation and cell survival. Mechanisms of Development 136, 8-29. PMCID: PMC4479208